Indications
GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is indicated
in patients with newly diagnosed high-grade malignant glioma as an adjunct to surgery
and radiation.
GLIADEL Wafer is also indicated in patients with recurrent glioblastoma multiforme
as an adjunct to surgery.
Important Safety Information
Patients undergoing craniotomy for malignant glioma and implantation of GLIADEL
Wafer should be monitored closely for known complications of craniotomy, including
seizures, intracranial infections, abnormal wound healing, and brain edema. Cases
of intracerebral mass effect unresponsive to corticosteroids have been described
in patients treated with GLIADEL Wafer, including 1 case leading to brain herniation.
Please see additional Important Safety Information below.
For US Healthcare Professionals Only